Friday, July 14

IC5
A Multiscale Model for Tumor Growth

9:15 AM - 10:00 AM
Room: Imperial Ballroom - ML
Chair: Trachette Jackson, University of Michigan, Ann Arbor

Cancer has become the leading cause of death for Americans. The development of prognostic tools could have immediate impact on the lives of millions of cancer patients. We have developed a multiscale model that integrates a cellular model for cell dynamics (cell growth, division, death, and cell-cell adhesion), an intracellular protein regulatory network for cell cycle control, and extracellular reaction-diffusion chemical dynamics. This model has produced tumor growth dynamics that agree with tumor spheroid experiments, and generated hypotheses on tumor biology that can be tested by experiments. This model framework can potentially predict tumor development and effects of therapies.

Yi Jiang
Los Alamos National Laboratory

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