Mathematical Models for Tissue Engineering Applications
The broad goal of tissue engineers is to grow functional tissues and organs in the laboratory to replace those which have become defective through age, trauma, and disease and which can be used in drug screening applications. To achieve this goal, tissue engineers aim to control accurately the biomechanical and biochemical environment of the growing tissue construct, in order to engineer tissues with the desired composition, biomechanical and biochemical properties (in the sense that they mimic the in vivo tissue). The growth of biological tissue is a complex process, resulting from the interaction of numerous processes on disparate spatio-temporal scales. Advances in the understanding of tissue growth processes promise to improve the viability and suitability of the resulting tissue constructs. In this talk, I highlight some of our recent mathematical modelling work that aims to provide insights into tissue engineering applications.
Sarah Waters, University of Oxford, United Kingdom