Dr. Ted A. Gooley
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N., D5-290
P.O. Box 19024
Seattle, WA 98109-1024
Ted Gooley (Ph.D., University of Arizona, 1990) has been employed as a biostatistician at the FHCRC since November 1992. Trained in applied mathematics, with an emphasis in statistical applications, he currently serves as a biostatistical consultant in the bone marrow transplant program at FHCRC. His duties involve the design and analysis of clinical trials in the bone marrow transplant field as well as developing new methodologies for analyzing data from clinical trials. Survival analysis and regression analysis are the primary tools that are used in these clinical trials. Prior to joining FHCRC, his thesis work was done in the area of statistical image reconstruction.
Some Basic Components of Design and Analysis of Clinical Trials in Oncology
In this talk, I shall give an overview of the goals of various stages of clinical trials, particularly trials in the setting of oncology. This will lead to discussion of design and analysis of such trials, and the potental difficulties of each. The talk will be largely non-technical, although basic concepts of probability and statistical methodology may aid in the understanding of the overall picture. Real-world examples from the Fred Hutchinson Cancer Research Center will be used to help illustrate design and analysis issues of clinical trials in the setting of bone marrow transplantation.